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Showing posts with label compacting morula. Show all posts
Showing posts with label compacting morula. Show all posts

Tuesday, March 24, 2015

My IVF Journey Timeline !


1. IVF ( October 2008)
Antagonist protocol
AMH-3.5
One month of BCP
Started stimulation on day 2 with 112.5 iu of Gonal F
Increased upto 150 iu until day 12
Before triggering e2 was only at 626
Only 3 eggs retrieved
Only one fertilized (through IVF)
Transfer on day 3- 4 celled embryo ( After transfer 8% crinone once a day, Progynova 4mg/ day and HCG booster dose)
Negative pregnancy test


2. IVF- ICSI (December 2008)
Antagonist protocol 
NO BCP
Metformin 1500 mg
Started stimulation on day 2 with 175 iu of Gonal F
Continued with same stimulation dosage for 11 days
e2 after 4 days after stimulation 140
e2 after 7 days after stimulation 375
e2 after 10 days after stimulation 1120
9 eggs retrieved
7 mature eggs – 3 eggs used for fertilization by IVF and 4 eggs used for fertilization by ICSI
In IVFed eggs none fertilized.
In ICSIed 2 eggs fertilized
Endometrial lining > 8mm
Both fertilized eggs grade A with 4 cells on day 2
Transferred both on day 2 (After transfer 8% crinone once a day, Progynova 4mg/ day and HCG booster dose)
Positive pregnancy test- m/c at 8 weeks- no HB detected. But had scan only on 5w1d and again on 9w1d. On 5w1d scan a sac measuring 6mm with no yolk sac or foetal pole. On 9w1d there is yolk sac and foetal pole but no HB. D&C March.

3. IVF-ICSI (July 2009)
Antagonist protocol 
AMH-4.5
One month of BCP
Metformin 1500mg
Started stimulation on day 2 with 175 iu of Gonal F
First u/s 6 days after stimulation – Only one follicle on right measuring > 24mm ovary and on the left some follicles and two of them are more than 20mm.
Stimulated for 11 days (?)
Only 5 eggs retrieved and only 2 are mature and both fertilzed with ICSI
On day 2 one embryo had 2 cell and the other 6 cell- Both garde C embryos
Transferred on day 2 – Negative pregnancy test (After transfer 8% crinone once a day, Progynova 4mg/ day , no booster HCG)
Endometrial lining 12mm
Negative pregnancy test.


4. IVF-ICSI (September 2009)
Flare protocol
NO BCP
Metformin 1500 mg
Started with synarel on day 2- twice a day
Then from day 3 Pergoveris ( 150 iu Gonal F+75 iu LH)
After 3 days of stimulation e2 at 101
After 6 of stimulation e2 at 212 ( But still spotted because of synarel ???)
Due to slow growing follicles and slow rising e2 dosage of Gonal F increased to 225iu+75 LH
So after further 3 days of stimulation e2 at 828
Stimulation continued for another 3 days with 300iu of Gonal F + 75 LH
So after 12 days of stimulation at retrieval 8 eggs retrieved
7 mature 7 ICSIed and all 7 fertilized
Transferred 3 embryos with AH and with embryo glue. AH done on day 2.
On day 2 - I had one 2 celled, one 3 celled and one 4 celled embryo.
day 3 transfer- 3 embryos- 1 compacting morula, 2 at 6 celled stage. ( No grade for morula since it is much advanced for day 3 and other 2 embryos grade B)
(After transfer 8% crinone once a day, Progynova 4mg/ day , no booster HCG)
Endometrial lining at 10mm. Added Heparin.
Started bleeding after 9dp3dt. Lots of cramping and lower back pain.
Pregnancy test negative.

FET ( October 2009)
There were 4 frozen embryos (slow freezing)
3 embryos transferred
Negative pregnancy test

5. IVF- ICSI ( January 2011)
Antogonist Protocol
NO BCP
Metformin 1500mg
Baseline scan- no cysts
Started on 187,5 iu Gonal F
After 4 days e2 at 213
Gonal F increased to 225 iu
After 6 days of stimulation e2 at 375
Gonal F continued at 225 iu
After 8 days of stimulation e2 at 656
Total 11 days of stimulation
5 eggs retrieved- All 5 mature
3 eggs fertilized with ICSI
Day 4 transfer- 3 embryos ( 2 compacted morula and one 8 cell grade c)
Pregnancy test negative

All the above 5 IVF cycles are performed in Wetzlar, Germany.

6. IVF-ICSI (at Malpani Infertility Clinic, Mumbai) (November 2011)
Long Lupron Protocol ( a modified version of long lupron)

AMH-1.8
DHEA 75mg (For 8 months)
No Metformin
Mdicines used : Lupron, Menogon, Cyclogest, Progynova
300 iu Menogon
24 eggs retrieved
20 fertilized
10 usable embryos 
7 embryos frozen (5 on day 3 and 2 on day 5)
3 Grade A embryos transferred
 Pregnancy test negative.

FET (June 2012) (at Malpani Infertility Clinic, Mumbai)
Problem with the growth of endometrial lining, after several days it grew to 7mm (took almost 3 weeks to grow to this thickness) Used G-CSF to improve lining.
Transferred 2 day 6 blastocysts
Pregnancy test negative

FET (June 2013) (at Malpani Infertility Clinic, Mumbai)
Thin lining, only 6.7mm at the time of embryo transfer.
Transferred 3 grade A day 3 embryos which are frozen in 2011. (at the age of 33)
Pregnancy test positive :)
First ultrasound showed twins :)
Completed 13 weeks successfully as of 11.9.2013, and so far so good !
Please keep me in your prayers !

Lost babies due to incompetent cervix at 20 weeks.

FET (March 2014) (at Malpani Infertility Clinic, Mumbai)
It was a surrogacy cycle.
Transferred two blastocysts to surrogate (these blastocysts were grown from day 3 embryos which are frozen and thawed during previous FET and frozen again on day 5)
Surrogate had a positive pregnancy test.
Week 6 ultrasound showed only a gestational sac measuring only 4 weeks old.
Surrogate miscarried !

7. IVF-ICSI (at Malpani Infertility Clinic, Mumbai) (May 2014)
Long Lupron Protocol ( a modified version of long lupron)

AMH-1.6
Vitamin D 12ng/ml
No Metformin
No DHEA
Mdicines used : Lupron, Menogon, Uterogest, Progynova
300 iu Menogon
21 eggs retrieved
19 fertilized
7 Blastocysts
One transferred to my uterus
6 frozen
Positive pregnancy test !

Our daughter Anisha arrived !




Anisha born on January 13th 2015





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