tag:blogger.com,1999:blog-4970758006706422699.post6938669362019459203..comments2024-02-14T13:29:46.876+01:00Comments on A Pursuit to Perpetuate My Genes: A comparison of CCRM's publication about blastocyst tranfer and blastocyst transfer after Comprehensive Chromosome Screening - are they biased?Manjuhttp://www.blogger.com/profile/09465166865789437941noreply@blogger.comBlogger8125tag:blogger.com,1999:blog-4970758006706422699.post-25186707663062378892014-05-06T03:55:58.568+02:002014-05-06T03:55:58.568+02:00There is a huge factor here...age. 25 year olds ...There is a huge factor here...age. 25 year olds have a 10x higher rate than the 40 year oldsglobetrotterhttps://www.blogger.com/profile/07395947672058878287noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-58097641513081678322013-01-11T01:39:44.286+01:002013-01-11T01:39:44.286+01:00Yeah, the miscarriage was kind of a disorienting e...Yeah, the miscarriage was kind of a disorienting experience. Rani and I have never been romanticists when it came to human gestation. We're excited about the long term elements of parenthood, not so much about the few years in which our child would be in its "larval state." <br /><br />But oddly, the miscarriage came down on us harder than we expected it could. Not so much because we anthropomorphized the embryo, but because we felt like our chance was slipping away. Our numbers were pretty bad for the first cycle with pretty poor odds, but that seems like it might be turning around, now. <br /><br />Thanks, always, for all of the advice!Danahttps://www.blogger.com/profile/11692756074193193644noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-58274437755809710462013-01-09T14:43:46.246+01:002013-01-09T14:43:46.246+01:00I am sorry that you people had to go through the d...I am sorry that you people had to go through the dreadful miscarriage. Miscarriage after IVF is even horrible. You wife is young and I am sure you will find success soon. Good Luck !<br /><br />If you have more than 5 blastocyts then I will think about CCS. But Dana, to be very truthful, I will rather freeze the embryos and transfer them sequentially instead of doing CCS !<br /><br />ManjuManjuhttps://www.blogger.com/profile/09465166865789437941noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-57977338726537049312013-01-08T15:21:02.408+01:002013-01-08T15:21:02.408+01:00Manju, no, we're not with CCRM. We're dow...Manju, no, we're not with CCRM. We're down in the southern U.S. and we're using a South Florida Clinic that has yielded pretty good results. My wife is 31. <br /><br />I'm curious about CCS because we may have more embryos in our next cycle than we did in our last cycle. Our previous cycle only yielded two, 3-day embryos because of egg quality issues. We didn't wait for blastocycsts. However, after a rigorous weight loss and exercise regiment and some new meds, our numbers look substantially better than they did before, so we suspect we might end up with some additional embryos if we're lucky. Our first cycle yielded a pregnancy, but we miscarried in the first trimester (likely due to aneuploidy). <br /><br />So yeah, if you only have two embryos, it seems to me like it doesn't matter, especially if you have already paid for the embryo transfer. Sure, it's aggravating to have to deal with the "fog of war," but with only two embryos, having that knowledge doesn't seem to influence the outcome very much. Danahttps://www.blogger.com/profile/11692756074193193644noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-64875696863804205692013-01-07T16:04:25.627+01:002013-01-07T16:04:25.627+01:00Dana, are you with CCRM ? How old is your wife ? W...Dana, are you with CCRM ? How old is your wife ? With 2 blastocysts I do not think there is a need for CCS. I don't think it will help in anyway. If they do CCS on the two blasties and in the most unfortunate scenario find that both are not genetically normal, you won't be going in for an ET. But, do all genetically abnormal embryos (as labelled by CCS) fail to develop into a normal baby ? Or do all CCS normal embryos will implant and result in a live birth ? So, why to bother about CCS ? Manjuhttps://www.blogger.com/profile/09465166865789437941noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-46980165113820220462013-01-07T14:39:16.260+01:002013-01-07T14:39:16.260+01:00Lol, Manju, I see you are pulling your hair out li...Lol, Manju, I see you are pulling your hair out like I do so often, trying to discern whether there was a difference in methodology between two different research documents which exhibit counterdictory results. It would seem to make sense that CCS would positively influence outcomes, but I'm wondering too whether it's a good idea to conduct CCS if you only have, say, 2 mature blastocysts. After all, if you only have 2 to implant both anyway, it shouldn't really matter. <br /><br />Also, I was curious, do you know how much CCS costs? During our first cycle, my wife and I didn't have CCS available to us. Danahttps://www.blogger.com/profile/11692756074193193644noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-43045631816961057152012-10-17T11:03:23.706+02:002012-10-17T11:03:23.706+02:00You have caught the point exactly : )
"If th...You have caught the point exactly : )<br /><br />"If there was higher implantation rate 12yrs back without CCS testing What necessitates it to be done now?"- This is my question too!<br /><br />YES, that is what I think too! But we have to wait and watch how the field of CCS develops and people should not get carried away by such super positive publications.Manjuhttps://www.blogger.com/profile/09465166865789437941noreply@blogger.comtag:blogger.com,1999:blog-4970758006706422699.post-23126174609176156822012-10-17T09:38:23.598+02:002012-10-17T09:38:23.598+02:00Would love to hear more lay-man discussion on this...Would love to hear more lay-man discussion on this topic. If there was higher implantation rate 12yrs back without CCS testing What necessitates it to be done now? Should I infer that such research publications are mostly biased to direct public / medical opinion to certain factors which the research group desires?Mithyahttps://www.blogger.com/profile/05278576009368006527noreply@blogger.com